Current use of gene chip requires various tedious steps such as
purification of DNA or RNA from tissues, amplification of gene sequences
and purification, hybridization, and scanning. This often requires
expensive chemicals, highly trained technicians, time and effort.
is interested in integration of all these steps such that one can simply
add a minute amount of blood sample on to a gene chip for diagnosis
of diseases (see the diagram below).
We are also using the surface technology which allows identification
of minute changes in gene sequences with high fidelity.
Note also that this technology does not involve elaborate lab-on-a-chip
technology. Our technology has potential for automation of diagnosis
by gene chip.
Once such a technology is established, we want to develop
chips for various infections diseases, cancer, etc.