2. Venue : B101 , Institute of Biomedical Science and Technology
3. Speaker : Hojae Bae, Ph.D. Assistant Professor
College of Animal Bioscience and Technology, Department of Bioindustrial Technologies, Konkuk University, Hwayang-dong, Kwangjin-gu, Seoul 143-701, Republic of Korea
Microengineered Biomaterials for Tissue Engineering Applications
The cellular environment plays an integral role in tissue function. Controlling the microarchitecture in engineered tissues can direct tissue morphogenesis, with the resultant cell behavior highly dependent on the construct’s mechanical, binding, degradation and geometrical properties. Micro- and nanoscale technologies are emerging as powerful tools for controlling the interaction between cells and their surroundings for biological studies, tissue engineering, and cell-based screening. In addition, hydrogel biomaterials have been increasingly used in various engineered tissue applications since they provide cells with a hydrated 3D microenvironment that mimics the native extracellular matrix. In this talk, I will outline various approaches developed that merges microscale techniques with hydrogel biomaterials for generating complex 3D tissue structures. In addition, I will describe the fabrication and the use of microscale hydrogels for tissue engineering by using a ‘top-down’ and a ‘bottom-up’ and approach.